FDA pulls Darvon off the market: confirms heart danger

The FDA asked for the discontinuation of the sales of all painkillers containing proxyphene, mostly known under the branded names of Darvon and Darvocet, because of the potential for serious heart problems.

If you are taking any painkiller that contains proxyphene, please contact your doctor to seek their advice.

Please be forewarned that the drug can cause withdrawal symptoms if you suddenly stop taking it. Talk to your doctor about how to taper off of it, and what else you could do to help manage your pain.

Brand names of proxyphene include but not limited to-

Darvon
Darvon-N
PP-Cap

Brand names that have a of combination of products

Balacet (containing Acetaminophen and Propoxyphene)
Darvocet A500 (containing Acetaminophen and Propoxyphene)
Darvocet-N (containing Acetaminophen and Propoxyphene)
Darvon Compound 32 (containing Aspirin, Caffeine, and Propoxyphene)
Darvon Compound-65 (containing Aspirin, Caffeine, and Propoxyphene)
PC-CAP (containing Aspirin, Caffeine, and Propoxyphene)
Propacet (containing Acetaminophen and Propoxyphene)
Propoxyphene Compound 65 (containing Aspirin, Caffeine, and Propoxyphene)
Wygesic (containing Acetaminophen and Propoxyphene)
Darvocet

Advertisements

Fentanyl Recall

Many chronic pain patients take extended-released medications to help regulate their pain. Similar to once a week birth control pills, extended-released pain medications give chronic pain patients a steady stream of medication without letting them worry about when to take their next dose. After all, it is always easier to manage your pain that it is to subdue it.

I have tried many types of extended-released medication, everything from birth control pills to topical lidocaine patches. Unlike short acting (2-4 hours) medications, extended-released meds can be difficult to tell when they are not working correctly. Hence, why I find this recall very important to tell you about.

This week Actavis Inc. announced a voluntary recall to the wholesale and retail levels only of 18 lots of Fentanyl Transdermal System 25 mcg/hour C-II patches manufactured for Actavis by Corium International in the United States. (via) The company said that they were unaware of any patients who had experienced adverse effects from the products. (via)Reports say that the patches are releasing the medication at a faster rate than intended. Patients treated with a patch that releases fentanyl faster than intended could experience symptoms of opioid overdose, including excessive sedation, respiratory depression, and apnea. (via)

Please read the following for more information:
Actavis Press Release: 21/OCT/2010
Med Page Today

All Wheels 4 Fibromyalgia

Who says you can’t do it? Follow the team as they race across America!

” A cycling team of four cyclists and 12 crew members will race nonstop for 3,000 miles across the United States in the world’s toughest bicycle race the Race Across America (RAAM). The race begins on June 12, 2010 in Oceanside, Calif. and ends in Annapolis, Maryland. The objective is to complete this coast-to-coast race in the fastest time the goal is 6 days!
Mission:
The team’s endeavor, however, goes beyond completing this rigorous race. All Wheels 4 Fibromyalgia is partnering with the National Fibromyalgia Association, and select sponsors in a shared ambition to raise awareness of fibromyalgia, a complex pain disorder that affects an estimated 10 million women, men and children in the U.S.
Products:
All Wheels 4 Fibromyalgia will be raising funds to support fibromyalgia research and community-based education programs for individuals affected by the disorder. The team’s goal is to raise $75,000 by June 12.” (via All Wheels for Fibromyalgia’s Facebook Page)

Here are all the links so you can get involved:
Follow them on twitter as the team speeds along! @allwheels4fibro

Photos from 2009 All Wheels 4 Fibro! on Picasa

Want to help? You can donate to the National Fibromyalgia Association.

Stanford Tests T3 for the Treatment of Fibromyalgia

nav_imageStanford Systems Neuroscience and Pain Lab does it again. Dr. Ian Carroll, MD, MS, and Dr. Jarred Younger, PhD are currently enrolling patients now in a new clinical trial to help fibromyalgia patients. Dr. Younger also worked on Stanford’s research of low dose Naltrexone for the treatment of fibromyalgia.

Stanford says on their site:(via)
“We are investigating whether the thyroid hormone T3 is one such treatment that may alleviate the symptoms of Fibromyalgia. There is significant overlap between the symptoms ofhypothyroidism (low thyroid hormone production), depression, chronic fatigue, and Fibromyalgia. Patients with low thyroid hormone production who have been treated with T3 for depression have had some improvement in symptoms.

This is the first study to examine whether T3 may help with the symptoms of Fibromyalgia. Studies such as this are a necessary step to having an investigational drug become a mainstream treatment. Your participation is a vital part of the search for an effective Fibromyalgia treatment.”

To understand how your thyroid works, here’s a great site:www.endocrineweb.com/thyfunction.html

I also found out about Dr. John C. Lowe. Here is a great interview with him about the subject on about.com.

To see any other clinical trials going on, looking at the clinical trials.gov page is always a good place stop.
Look here to see what they have to say about the study.

Click here to see Stanford enrollment form -> http://snapl.stanford.edu/t3/

Also, check out Lumigrate’s educational video: Hypothyroidism: Misunderstood, Misdiagnosed, Missed! by Dr. Scott Rollins lum-hypothyroid_0

Discrimination law suit won!

t57925_13Good news today! An historic case was won in the Fifth Circuit Court of Appeals, EEOC v. Chevron Phillips. The EEOC sued Lorin Netterville’s former employer claiming violations of the Americans with Disabilities Act (ADA). The trial court granted summary judgment for the employer; the 5th Circuit reversed it.

Netterville is affected with CFS (Chronic Fatigue Syndrome). Her illness was is remission, and she was fired when it relapsed on her after 17 years. Her old employer said that she allegedly falsified her job-required medical evaluation.
The court ruled against the company, saying:

* The questions didn’t specifically include ME/CFS as a condition,
* and after 17 symptom-free years, a reasonable person wouldn’t likely understand that ME/CFS might be included in the category of “blood conditions.” (via)

This is one of the first law suits I have read about that helps us in our fight! It is so hard to prove our invisible illnesses. Even in this economy, it is nice to know that we do have equal rights!

for more information on this case please read about it here:
About.com

Law Memo Blog

For more info on your rights:
About.com and American Disabilities Act

Men and fibro

I love my father for more reasons than I can count. He is by far the greatest man I have ever known. My father has stood by me through all of my endeavors. During all the ups and downs with fibro, my Dad is there to hold my hand, wipe my tears, and make me laugh. But, I do wonder how my health condition effects him?

mhnThe Men’s Health Network is conducting a survey to gauge just that. They have teamed together with the American Pain Foundation and National Fibromyalgia Association to conduct this survey nationwide. Fibromyalgia is typically labeled a “women’s” disease. However, it does not discriminate, and men are affected by it too. Only about 10-20% of all fibro patients are male. Men are raised to be strong and not show pain. Overall, males tend to be less vocal about their health condition. The associations conducting this survey believe the numbers of recorded male patients affected with fibro is not accurate.

If you want to learn more about the survey, please click on the following link:
www.menshealthnetwork.org/fmsurvey.php.

News articles about this:
Medical News Service (posted 8/19)

PR News Wire (posted 8/18)

The National Fibromyalgia Association goes big on social media

n27225676432_9769I have been a member of the National Fibromyalgia Association for some time now. They are a wonderful organization to gain insight and find resources.

Please take a minute of your time to watch this short video from Lynne Matallana, president and founder of the National Fibromyalgia Association:

Or, you can read the email I received from them:

“The National Fibromyalgia Association launches campaign to reach
10,000 Facebook Fans by October 1.

ANAHEIM, Calif. (Aug. 3, 2009)—The National Fibromyalgia (NFA) has launched a campaign to get 10,000 “fans” on their Facebook Page by October 1, 2009. (A Facebook Page is an organization’s public profile that allows them to share news and announcements with Facebook users. “Fans” are Facebook users who follow the organization’s posts and are able to share them with their own network.)

The campaign, called “10,000 for 10 Million,” refers to the 10 million people in the U.S. who are suffering with fibromyalgia, the complex chronic pain disorder usually characterized by chronic widespread pain, multiple tender points, abnormal pain processing, sleep disturbances, fatigue and often psychological distress.

“10,000 for 10 Million” is the NFA’s first major social media campaign on Facebook, and aims to raise awareness of fibromyalgia and the National Fibromyalgia Association through the popular social networking site which attracts over 90 million visitors per month.

Lynne Matallana, president and founder of the National Fibromyalgia Association, admits that with just two months to reach their target goal of 10,000, the campaign is ambitious. However, the need to bring awareness, help and hope to those suffering with fibromyalgia is even greater.

“We want to let as many people as possible know about fibromyalgia and the NFA, and Facebook is one of the most powerful ways to do that,” explains Matallana. “We also want to empower the fans to share this information with their friends and family members. It takes just one or a few clicks on your keyboard to become a fan of the NFA’s Fan Page or to share the page with your Facebook friends, but those few clicks go a long way to show support for those 10 million people suffering with this disorder.”

When I logged on to Facebook today, they are less than 1,000 fans away from their goal of “10,000 for 10 million” campaign!

Let’s help them reach their goal!
You can reach The National Fibromyalgia Association at www.fmaware.org to become a member of the organization.

To become a “fan” of the NFA’s Facebook Fan Page, go to: http://www.thefibromyalgiaassociation.org/ and click on the Facebook icon. (NOTE: New Facebook users must first sign up on the Facebook homepage before accessing pages.)
or click on here

The sky is the limit on where these social connections can go!

Coming soon to a pharmacy near you: generic pain meds!

In the world of pain management, we have to take the good with the bad. And sometimes with all the treatments we have to make ourselves feel better, the bad part of pain medications out way the good. Their level of toxic-feeling side effects, then the medications we take to lessen those side effects, and of course the price of these medications all add up to their negative points. One insurance company will pay for a medication, where another won’t. When they don’t cover it, you cry at the price. But, it’s always an issue to cry then when you write the check for the pain medication, or cry later when you are rolling on the floor dying in pain at home. With all the endless variables of what is going to work for your condition, you might just as well play the lotto- you might have better luck.

There is hope because this strange field of pain medications and their side effects is going to change sooner than we think. The pain management world is big money business. Which, for us means that they will keep trying new medications and therapies for us. Years ago, Endo labs made a break through with their Lidoderm patch, thus changing the way pain relief was given to a patient. The topical patch gave relief over the course of a day with little to no side effects. Now, Endo is facing the big challenge of the Lidoderm patch coming in generic form. Great for us, less money! Bad for Endo.

The research field will keep advancing in the field of pain management. Business analysis say that this trend will keep growing for the next 3-5 years! We will see an increase in generic pain medications. Even though many of the branded medications have been the fore-runners in the treatments, its time they stepped aside. New treatments will be pushing their way into the market, and making their mark to help many patients find relief. Many of these will not cost as much as their older competitors, which is a great advantage in this recession.

According to one report (via), many of the new drugs hitting the market are reducing their R and D They are building off of brands they already have in production, either by line extensions or expanded formulations. They have learned what they need to know by the medications they have on the market and are just expanding on them. This will help build companies into being more specialized in the pain management arena, and make use of their products with expired patents.

Hopefully, with many more players in the pain management research field, we will have medications that cost us less, with better results and with less side effects! After all life is short, and I want to live every moment to the fullest!
Read more of this post

RLS: Gene mutation found

images-3Fibromyalgia patients commonly also suffer from RLS (Restless Leg Syndrome). This past week in Wheeling, W.VA scientist discovered the first ever gene mutation to be associated with RLS. Researches say that it is a functional gene mutation, found on the MEIS1 gene, which plays a vital role in development.
Another break-though is that the MEIS1 gene mutation, even though it is very rare, was found in family members who all had RLS.
For a while now, scientists have touched on the notion that fibromyalgia could have genetic links. The syndrome is commonly seen passed down on the maternal side of the family.
RLS researchers also found a mutation in gene BTBD9. These mutations combined with MEIS1 mutations showed up together on RLS patients more than the general public. But, this genetic combo mutation is thought to be non-functional.

For more info, please visit medpagetoday

%d bloggers like this: